Anti-Heat Shock Protein 60 (HSP60, GroEL, Chaperonin 60, cpn60 (D307)

Anti-Heat Shock Protein 60 (HSP60, GroEL, Chaperonin 60, cpn60 (D307)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
H1834-25J.100 100 µl - -

3 - 19 business days

505.00€
 
In both prokaryotic and eukaryotic cells the misfolding and aggregation of proteins during... more
Product information "Anti-Heat Shock Protein 60 (HSP60, GroEL, Chaperonin 60, cpn60 (D307)"
In both prokaryotic and eukaryotic cells the misfolding and aggregation of proteins during biogenesis and under conditions of cellular stress are prevented by molecular chaperones (1-3). HSP60 has primarily been known as a mitochondrial protein that is important for folding key proteins after import into the mitochondria (4). It is now clear that a significant amount of HSP60 is also present in the cytosol of many cells and that it is induced by stress, inflammatory and immune responses, autoantibodies correlated with Alzheimer's, coronary artery diseases, MS, and diabetes (5-8). Applications: Suitable for use in Flow Cytometry, Immunofluorescence and Western Blot. Other applications have not been tested. Recommended Dilutions: Western Blot: 1:1000, incubate membrane with diluted antibody in 5% BSA, 1X TBS, 0.1% Tween-20 at 4°C with gentle shaking, overnight. , Immunofluorescence (IF-IC): 1:50 , Flow Cytometry: 1:50 , Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Supplier: United States Biological
Supplier-Nr: H1834-25J

Properties

Application: FC, IF, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Drosophila, Human, Monkey, Mouse, Rat
Immunogen: Synthetic peptide (KLH-coupled) surrounding Asp307 of human HSP60.
Purity: Purified by Protein A affinity chromatography.
Format: Affinity Purified

Database Information

Handling & Safety

Storage: -20°C (-20°C Glycerol)
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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