Anti-HCG-beta (Pregnancy & Choriocarcinoma Marker) Recombinant Mouse Monoclonal Antibody (clone:rHCG

Anti-HCG-beta (Pregnancy & Choriocarcinoma Marker) Recombinant Mouse Monoclonal Antibody (clone:rHCG
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ABE-12-1187-100 100 µg -

3 - 11 business days*

661.00€
 
This MAb reacts with a protein of 22kDa, identified as beta sub-unit of HCG. It does not cross... more
Product information "Anti-HCG-beta (Pregnancy & Choriocarcinoma Marker) Recombinant Mouse Monoclonal Antibody (clone:rHCG"
This MAb reacts with a protein of 22kDa, identified as beta sub-unit of HCG. It does not cross react with the alpha sub-unit. HCG is a glycoprotein, which is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG is composed of two non-identical, non-covalently linked polypeptide chains designated as the and subunits. The subunit is identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH), and luteinizing hormone (LH). hCG MAb detects cells and tumors of trophoblastic origin such as choriocarcinoma. Large cell carcinoma and adenocarcinoma of the lung demonstrate anti-hCG positivity in 90% and 60% of cases respectively. 20% of lung squamous cell carcinomas are positive. hCG expression by non-trophoblastic tumors may indicate aggressive behavior. Protein function: Beta subunit of the human chorionic gonadotropin (hCG). hCG is a complex glycoprotein composed of two glycosylated subunits alpha and beta which are non-covalently associated. The alpha subunit is identical to those in the pituitary gonadotropin hormones (LH, FSH and TSH). The beta subunits are distinct in each of the hormones and confer receptor and biological specificity. Has an essential role for pregnancy and maternal adaptation. Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. [The UniProt Consortium]
Keywords: Anti-Choriogonadotropin subunit beta 7, Anti-HCG-beta (Pregnancy & Choriocarcinoma Marker) Recombinant Mouse Monoclonal Antibody (Clone:rHCGb/54)
Supplier: Abeomics
Supplier-Nr: 12-1187

Properties

Application: IHC
Antibody Type: Monoclonal
Clone: rHCGb/54
Conjugate: No
Host: Mouse
Reactivity: Human
Immunogen: Recombinant full-length hCG beta protein
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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