Anti-H2AX Recombinant Monoclonal

Item number Size Datasheet Manual SDS Delivery time Quantity Price
A700-059-T 10 µl (5+ tests) -

2 - 8 business days*

172.00€
A700-059 100 µl (50+ tests) -

2 - 8 business days*

655.00€
 
Protein function: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.... more
Product information "Anti-H2AX Recombinant Monoclonal"
Protein function: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C- terminal phosphorylation. [The UniProt Consortium]
Keywords: Anti-H2AX, Anti-H2a/x, Anti-H2AFX, Anti-Histone H2AX, Anti-Histone H2A.X
Supplier: Bethyl Laboratories
Supplier-Nr: A700-059

Properties

Application: WB, IHC, ICC, FC
Antibody Type: Monoclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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