Anti-h/m CD11b (Clone: M1/70) FITC conjugated

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Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Discount	Price
ABE-10-4158-F-100	100 µg		-		3 - 11 business days*		15 %	290.00€ 246.50€

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Protein function: Integrin ITGAM/ITGB2 is implicated in various adhesive interactions of... more

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Product information "Anti-h/m CD11b (Clone: M1/70) FITC conjugated"

Protein function: Integrin ITGAM/ITGB2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles and pathogens. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin ITGAM/ITGB2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain. Regulates neutrophil migration. In association with beta subunit ITGB2/CD18, required for CD177-PRTN3-mediated activation of TNF primed neutrophils. May regulate phagocytosis-induced apoptosis in extravasated neutrophils. May play a role in mast cell development. [The UniProt Consortium]

Keywords:	Anti-Itgam, Anti-CD11b, Anti-Integrin alpha-M, Anti-CR-3 alpha chain, Anti-Leukocyte adhesion receptor MO1, Anti-CD11 antigen-like family member B, Anti-Cell surface glycoprotein MAC-1 subunit alpha, Monoclonal Antibody to h/m CD11b (Clone: M1/70) FITC co
Supplier:	Abeomics
Supplier-Nr:	10-4158-F

Properties

Application:	FC
Antibody Type:	Monoclonal
Clone:	M1/70
Conjugate:	FITC
Host:	Rat
Species reactivity:	mouse
Immunogen:	B10 mouse spleen cells enrichedfor T lymphocytes were used as immunogen for this antibody.
Format:	Purified