Anti-GSTM5, NT (GSTM5, Glutathione S-transferase Mu 5, GST class-mu 5, GSTM5-5)

Anti-GSTM5, NT (GSTM5, Glutathione S-transferase Mu 5, GST class-mu 5, GSTM5-5)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
036341.200 200 µl - -

3 - 19 business days*

728.00€
 
Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct... more
Product information "Anti-GSTM5, NT (GSTM5, Glutathione S-transferase Mu 5, GST class-mu 5, GSTM5-5)"
Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Diversification of these genes has occurred in regions encoding substrate-binding domains, as well as in tissue expression patterns, to accommodate an increasing number of foreign compounds. Applications: Suitable for use in Western Blot, Immunohistochemistry, Flow Cytometry, ELISA, Recommended Dilution: ELISA: 1:1,000, Western Blot: 1:100-500, Immunohistochemistry: 1:10-50, Flow Cytometry: 1:10-50, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: Anti-GSTM5, Anti-GSTM5-5, EC=2.5.1.18, Anti-GST class-mu 5, Anti-Glutathione S-transferase Mu 5
Supplier: United States Biological
Supplier-Nr: 036341

Properties

Application: ELISA, FC, IHC, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: GSTM5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-51 amino acids from the N-terminal region of human GSTM5.
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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