Anti-GSTA3

Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-AB-11286.20 20 µl -

7 - 16 business days*

71.00€
E-AB-11286.60 60 µl -

7 - 16 business days*

143.00€
E-AB-11286.120 120 µl -

7 - 16 business days*

238.00€
E-AB-11286.200 200 µl -

7 - 16 business days*

396.00€
 
Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct... more
Product information "Anti-GSTA3"
Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class genes that are located in a cluster mapped to chromosome 6. Genes of the alpha class are highly related and encode enzymes with glutathione peroxidase activity. However, during evolution, this alpha class gene diverged accumulating mutations in the active site that resulted in differences in substrate specificity and catalytic activity. Protein function: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Catalyzes isomerization reactions that contribute to the biosynthesis of steroid hormones. Efficiently catalyze obligatory double-bond isomerizations of delta(5)-androstene-3,17-dione and delta(5)- pregnene-3,20-dione, precursors to testosterone and progesterone, respectively. [The UniProt Consortium]
Keywords: Anti-GSTA3, EC=2.5.1.18, Anti-GST class-alpha member 3, Anti-Glutathione S-transferase A3, Anti-Glutathione S-transferase A3-3, GSTA3 Polyclonal Antibody
Supplier: Elabscience
Supplier-Nr: E-AB-11286

Properties

Application: WB, IHC, ELISA
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: Recombinant protein of human GSTA3
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: 4°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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