Anti-GRPR, ID (GRPR, Gastrin-releasing peptide receptor, GRP-preferring bombesin receptor) (Azide fr

Anti-GRPR, ID (GRPR, Gastrin-releasing peptide receptor, GRP-preferring bombesin receptor) (Azide fr
Item number Size Datasheet Manual SDS Delivery time Quantity Price
036320-HRP.200 200 µl - -

3 - 19 business days*

721.00€
 
Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central... more
Product information "Anti-GRPR, ID (GRPR, Gastrin-releasing peptide receptor, GRP-preferring bombesin receptor) (Azide fr"
Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues. The effects of GRP are mediated through the gastrin-releasing peptide receptor. This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway. The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate. An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene. Applications: Suitable for use in ELISA and Immunohistochemistry. Other applications have not been tested. Recommended Dilutions: Immunohistochemistry: Formalin-fixed, paraffin-embedded tissues, Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. , , Note: Applications are based on unconjugated antibody.
Keywords: Anti-GRPR, Anti-GRP-R, Anti-GRP-preferring bombesin receptor, Anti-Gastrin-releasing peptide receptor
Supplier: United States Biological
Supplier-Nr: 036320-HRP

Properties

Application: ELISA, IHC
Antibody Type: Polyclonal
Conjugate: HRP
Host: Rabbit
Reactivity: Human
Immunogen: GRPR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 130~160 amino acids from the Central region of human GRPR.
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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