Anti-GRM1, CT (GRM1, GPRC1A, MGLUR1, Metabotropic glutamate receptor 1) (Azide free) (HRP)

Anti-GRM1, CT (GRM1, GPRC1A, MGLUR1, Metabotropic glutamate receptor 1) (Azide free) (HRP)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
036313-HRP.200 200 µl - -

3 - 19 business days*

721.00€
 
L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates... more
Product information "Anti-GRM1, CT (GRM1, GPRC1A, MGLUR1, Metabotropic glutamate receptor 1) (Azide free) (HRP)"
L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. The canonical alpha isoform of the metabotropic glutamate receptor 1 gene is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system. Alternative splicing results in multiple transcript variants encoding distinct isoforms, some of which may have distinct functions. [provided by RefSeq]. Applications: Suitable for use in Western Blot, ELISA, Recommended Dilution: ELISA: 1:1,000, Western Blot: 1:100-500, Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. , , Note: Applications are based on unconjugated antibody.
Keywords: Anti-GRM1, Anti-GPRC1A, Anti-mGluR1, Anti-Metabotropic glutamate receptor 1
Supplier: United States Biological
Supplier-Nr: 036313-HRP

Properties

Application: ELISA, WB
Antibody Type: Polyclonal
Conjugate: HRP
Host: Rabbit
Reactivity: Human
Immunogen: GRM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1094-1123 amino acids from the C-terminal region of human GRM1.
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow. more
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "Anti-GRM1, CT (GRM1, GPRC1A, MGLUR1, Metabotropic glutamate receptor 1) (Azide free) (HRP)"
Write a review
or to review a product.
Viewed