Anti-Granzyme B, clone GZB-1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
NSJ-V7638-20UG	20 µg		-	-	3 - 10 business days*		332.00€
NSJ-V7638-100UG	100 µg		-	-	3 - 10 business days*		752.00€

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0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide. This enzyme is necessary for... more

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Product information "Anti-Granzyme B, clone GZB-1"

0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide. This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis. [UniProt] Protein function: This enzyme is necessary for target cell lysis in cell- mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis. [The UniProt Consortium]

Keywords:	Anti-HLP, Anti-C11, Anti-SECT, Anti-CGL1, Anti-GZMB, Anti-CTLA-1, Anti-CTSGL1, Anti-Granzyme-2, Anti-Granzyme B, Anti-Fragmentin-2, EC=3.4.21.79, Anti-Cathepsin G-like 1, Anti-Lymphocyte protease, Anti-Human lymphocyte protein, Granzyme B Antibody
Supplier:	NSJ Bioreagents
Supplier-Nr:	V7638

Properties

Application:	WB, IHC (paraffin)
Antibody Type:	Monoclonal
Clone:	GZB-1
Conjugate:	No
Host:	Mouse
Species reactivity:	human
Immunogen:	Amino acids 73-187
Format:	Purified