Anti-GP6, CT (GP6, Platelet glycoprotein VI, Glycoprotein 6) (Azide free) (FITC)

Anti-GP6, CT (GP6, Platelet glycoprotein VI, Glycoprotein 6) (Azide free) (FITC)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
036184-FITC.200 200 µl - -

3 - 19 business days*

721.00€
 
Glycoprotein VI (GP6) is a 58-kD platelet membrane glycoprotein that plays a crucial role in the... more
Product information "Anti-GP6, CT (GP6, Platelet glycoprotein VI, Glycoprotein 6) (Azide free) (FITC)"
Glycoprotein VI (GP6) is a 58-kD platelet membrane glycoprotein that plays a crucial role in the collagen-induced activation and aggregation of platelets. Upon injury to the vessel wall and subsequent damage to the endothelial lining, exposure of the subendothelial matrix to blood flow results in deposition of platelets. Collagen fibers are the most thrombogenic macromolecular components of the extracellular matrix, with collagen types I, III, and VI being the major forms found in blood vessels. Platelet interaction with collagen occurs as a 2-step procedure: (1) the initial adhesion to collagen is followed by (2) an activation step leading to platelet secretion, recruitment of additional platelets, and aggregation. In physiologic conditions, the resulting platelet plug is the initial hemostatic event limiting blood loss. However, exposure of collagen after rupture of atherosclerotic plaques is a major stimulus of thrombus formation associated with myocardial infarction or stroke (Jandrot-Perrus et al., 2000 [PubMed 10961879]). Applications: Suitable for use in FLISA, Western Blot and Flow Cytometry. Other applications have not been tested. , Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap., , Note: Applications are based on unconjugated antibody.
Keywords: Anti-GP6, Anti-GPVI, Anti-Glycoprotein 6, Anti-Platelet glycoprotein VI
Supplier: United States Biological
Supplier-Nr: 036184-FITC

Properties

Application: FC, WB
Antibody Type: Polyclonal
Conjugate: FITC
Host: Rabbit
Reactivity: Human
Immunogen: GP6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 316-345 amino acids from the C-terminal region of human GP6.
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow. more
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "Anti-GP6, CT (GP6, Platelet glycoprotein VI, Glycoprotein 6) (Azide free) (FITC)"
Write a review
or to review a product.
Viewed