Anti-GNA13

Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-AB-14089.20 20 µl -

7 - 16 business days*

71.00€
E-AB-14089.60 60 µl -

7 - 16 business days*

143.00€
E-AB-14089.120 120 µl -

7 - 16 business days*

238.00€
E-AB-14089.200 200 µl -

7 - 16 business days*

396.00€
 
Guanine nucleotide-binding protein subunit alpha-13 is a protein that in humans is encoded by the... more
Product information "Anti-GNA13"
Guanine nucleotide-binding protein subunit alpha-13 is a protein that in humans is encoded by the GNA13gene. Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G proteins are composed of 3 units, alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site. Interacts with UBXD5. Interacts with HAX1. Interacts (when active) with PPP5C (via TPR repeats), activates PPP5C phosphatase activity and translocates PPP5C to the cell membrane. Protein function: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems (PubMed:15240885, PubMed:16787920, PubMed:16705036, PubMed:27084452). Activates effector molecule RhoA by binding and activating RhoGEFs (ARHGEF1/p115RhoGEF, ARHGEF11/PDZ-RhoGEF and ARHGEF12/LARG) (PubMed:15240885, PubMed:12515866). GNA13-dependent Rho signaling subsequently regulates transcription factor AP-1 (activating protein-1). Promotes tumor cell invasion and metastasis by activating RhoA/ROCK signaling pathway (PubMed:16787920, PubMed:16705036, PubMed:27084452). Inhibits CDH1-mediated cell adhesion in process independent from Rho activation (PubMed:11976333). [The UniProt Consortium]
Keywords: Anti-GNA13, Anti-G alpha-13, Anti-G-protein subunit alpha-13, Anti-Guanine nucleotide-binding protein subunit alpha-13, GNA13 Polyclonal Antibody
Supplier: Elabscience
Supplier-Nr: E-AB-14089

Properties

Application: WB, IHC, ELISA
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat
Immunogen: Recombinant protein of human GNA13
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: 4°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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