Anti-Glucose Regulated Protein 94 (Grp94, gp96, ECGP, Endoplasmin, Heat Shock Protein 90kD beta Memb

Anti-Glucose Regulated Protein 94 (Grp94, gp96, ECGP, Endoplasmin, Heat Shock Protein 90kD beta Memb
Item number Size Datasheet Manual SDS Delivery time Quantity Price
G3057-40J.100 100 µg - -

3 - 19 business days*

629.00€
 
GRP94 is a 803aa protein belonging to the heat shock protein 90 family. It acts as a molecular... more
Product information "Anti-Glucose Regulated Protein 94 (Grp94, gp96, ECGP, Endoplasmin, Heat Shock Protein 90kD beta Memb"
GRP94 is a 803aa protein belonging to the heat shock protein 90 family. It acts as a molecular chaperone that functions in the processing and transport of secreted proteins. GRP94 and its N-terminal fragment stimulates CTL expansion and maturation of human monocyte-derived dendritic cells (MDDC). It plays a central role in innate as well as acquired immunity, maturation and chemotaxis of dendritic cells, Ab production, cross-priming, as a potential marker in breast cancer and is a peptide acceptor in endoplasmic reticulum and an accessory to peptide loading of MHC class I molecules. Expression of GRP94 suppressed A23187-induced apoptosis and stabilized calcium homeostasis. GRP94 is expressed in melanoma or liver metastases of colon carcinoma cells, human gastric carcinoma BGC-823 cells. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: 0.5-2ug/ml, Immunohistochemistry (paraffin): 10ug/ml, Optimal dilutions to be determined by the researcher. Positive Control: 3T3 and RAW cell lysate, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: Anti-GRP-94, Anti-gp96 homolog, Anti-Tumor rejection antigen 1, Anti-94 kDa glucose-regulated protein, Anti-Heat shock protein 90 kDa beta member 1
Supplier: United States Biological
Supplier-Nr: G3057-40J

Properties

Application: IHC, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: horse, human, monkey, mouse
Immunogen: Synthetic peptide corresponding to aa590-640 of human GRP94.
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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