Anti-GAPDH Recombinant Monoclonal

Item number Size Datasheet Manual SDS Delivery time Quantity Price
A700-103-T 10 µl (5+ tests) -

3 - 9 business days*

131.00€
A700-103 100 µl (50+ tests) -

3 - 9 business days*

493.00€
 
Protein function: Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities,... more
Product information "Anti-GAPDH Recombinant Monoclonal"
Protein function: Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubules. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3- phospho-D-glyceroyl phosphate. Component of the GAIT (gamma interferon- activated inhibitor of translation) complex which mediates interferon- gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma treatment assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation. [The UniProt Consortium]
Keywords: Anti-GAPD, Anti-GAPDH, Anti-CDABP0047, EC=2.6.99.-, EC=1.2.1.12, Anti-Peptidyl-cysteine S-nitrosylase GAPDH, Anti-Glyceraldehyde-3-phosphate dehydrogenase
Supplier: Bethyl Laboratories
Supplier-Nr: A700-103

Properties

Application: WB, IHC, ICC
Antibody Type: Monoclonal
Conjugate: No
Host: Rabbit
Reactivity: Human, Mouse
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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