Anti-GAPDH

Item number Size Datasheet Manual SDS Delivery time Quantity Price
A300-639A-T 20 µl (2 blots) -

3 - 9 business days*

131.00€
A300-639A-M 100 µl (10 blots) -

3 - 9 business days*

313.00€
A300-639A 100 µl (20 µg) -

3 - 9 business days*

465.00€
 
Protein function: Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities,... more
Product information "Anti-GAPDH"
Protein function: Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubules. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D- glyceroyl phosphate. Component of the GAIT (gamma interferon- activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma treatment assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation. [The UniProt Consortium]
Keywords: Anti-GAPD, Anti-GAPDH, Anti-CDABP0047, EC=1.2.1.12, EC=2.6.99.-, Anti-Peptidyl-cysteine S-nitrosylase GAPDH, Anti-Glyceraldehyde-3-phosphate dehydrogenase
Supplier: Bethyl Laboratories
Supplier-Nr: A300-639A

Properties

Application: WB, IP, IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human, Mouse (Expected: Rat, Zebrafish, Chicken, Sheep, Bovine, Rabbit, Guinea Pig_10141, Pig, Golden Hamster, Cat, Orangutan)
Immunogen: synthetic peptide. The epitope recognized by A300-639A-T maps to a region between residues 150 and 200 of human Glyceraldehyde-3-Phosphate Dehydrogenase using the numbering given in entry NP_002037.2 (GeneID 2597).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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