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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Discount | Price |
---|---|---|---|---|---|---|---|---|
AG-20B-0005-C100 | 100 µg | - |
3 - 9 business days* |
10 %
|
462.00€
415.80€ |
Recognizes an epitope (aa 1-200) present in both short (FLIPS) and long (FLIPL) splice variants... more
Product information "Anti-FLIP, clone Dave-2"
Recognizes an epitope (aa 1-200) present in both short (FLIPS) and long (FLIPL) splice variants of human and mouse FLIP. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. FLIP is an apoptosis regulator protein which functions as a crucial link between cell survival and cell death pathways in mammalian cells and acts as an inhibitor of TNFRSF6 mediated apoptosis. A proteolytic fragment (p43) is likely retained in the death-inducing signaling complex (DISC) thereby blocking further recruitment and processing of caspase-8 at the complex. Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis. FLIP lacks enzymatic (caspase) activity. FLIP is highly expressed in skeletal muscle, pancreas, heart, kidney, placenta and peripheral blood leukocytes.
Keywords: | I-FLICE, CLARP, CASPER, Usurpin, CASH, FLAME-1 |
Supplier: | AdipoGen Life Sciences |
Supplier-Nr: | AG-20B-0005 |
Properties
Application: | IP, WB |
Antibody Type: | Monoclonal |
Clone: | Dave-2 |
Conjugate: | No |
Host: | Rat |
Species reactivity: | human , mouse |
Immunogen: | Recombinant human FLIP (aa 1-480). |
Format: | Purified |
Database Information
KEGG ID : | K04724 | Matching products |
UniProt ID : | O15519 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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You will get a certificate here
-10 %
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