Anti-FLIP, clone Dave-2

Anti-FLIP, clone Dave-2
%
Item number Size Datasheet Manual SDS Delivery time Quantity Discount Price
AG-20B-0005-C100 100 µg -

3 - 9 business days*

10 %
462.00€
415.80€
 
Recognizes an epitope (aa 1-200) present in both short (FLIPS) and long (FLIPL) splice variants... more
Product information "Anti-FLIP, clone Dave-2"
Recognizes an epitope (aa 1-200) present in both short (FLIPS) and long (FLIPL) splice variants of human and mouse FLIP. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. FLIP is an apoptosis regulator protein which functions as a crucial link between cell survival and cell death pathways in mammalian cells and acts as an inhibitor of TNFRSF6 mediated apoptosis. A proteolytic fragment (p43) is likely retained in the death-inducing signaling complex (DISC) thereby blocking further recruitment and processing of caspase-8 at the complex. Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis. FLIP lacks enzymatic (caspase) activity. FLIP is highly expressed in skeletal muscle, pancreas, heart, kidney, placenta and peripheral blood leukocytes.
Keywords: I-FLICE, CLARP, CASPER, Usurpin, CASH, FLAME-1
Supplier: AdipoGen Life Sciences
Supplier-Nr: AG-20B-0005

Properties

Application: IP, WB
Antibody Type: Monoclonal
Clone: Dave-2
Conjugate: No
Host: Rat
Species reactivity: human , mouse
Immunogen: Recombinant human FLIP (aa 1-480).
Format: Purified

Database Information

KEGG ID : K04724 | Matching products
UniProt ID : O15519 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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