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Protein function: May play a role as coactivator in transcriptional activation by hormone-activated nuclear receptors (NR) and acts in cooperation with NCOA2 and CARM1. Involved in estrogen hormone signaling. Involved in early embryonic development. May play a role in regulation of cytoskeletal rearrangements involved in cytokinesis and cell migration, by inhibiting Rac1-dependent paxillin phosphorylation. [The UniProt Consortium]
synthetic peptide. The epitope recognized by A301-565A-T maps to a region between residue 425 and 475 of human Flightless-1 using the numbering given in entry NP_002009.1 (GeneID 2314).
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