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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ABE-12-1181-20 | 20 µg | - |
3 - 11 business days* |
373.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Filaggrin is an intermediate filament-associated protein that aggregates keratin intermediate... more
Product information "Anti-Filaggrin (Keratinocyte Differentiation Marker) Recombinant Rabbit Monoclonal Antibody (clone:F"
Filaggrin is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules. Active filaggrin is present at a level of the epidermis where keratinocytes are in transition between the live nucleated granular layer and the anucleate cornified layer, sµggesting that filaggrin aids in the terminal differentiation process by facilitating apoptotic machinery. Protein function: Aggregates keratin intermediate filaments and promotes disulfide-bond formation among the intermediate filaments during terminal differentiation of mammalian epidermis. [The UniProt Consortium]
Keywords: | Anti-FLG, Anti-Filaggrin, Anti-Filaggrin (Keratinocyte Differentiation Marker) Recombinant Rabbit Monoclonal Antibody (Clone:FLG/1957R) |
Supplier: | Abeomics |
Supplier-Nr: | 12-1181-20 |
Properties
Application: | IHC |
Antibody Type: | Monoclonal |
Clone: | FLG/1957R |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | Recombinant fragment of human Filaggrin protein (aa 198-288) (exact sequence is proprietary) |
Format: | Purified |
Database Information
KEGG ID : | K10384 | Matching products |
UniProt ID : | P20930 | Matching products |
Gene ID | GeneID 2312 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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You will get a certificate here
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