Anti-Filaggrin (Keratinocyte Differentiation Marker) Recombinant Rabbit Monoclonal Antibody (clone:F

Item number Size Datasheet Manual SDS Delivery time Quantity Price
ABE-12-1181-100 100 µg -

3 - 11 business days*

850.00€
 
Filaggrin is an intermediate filament-associated protein that aggregates keratin intermediate... more
Product information "Anti-Filaggrin (Keratinocyte Differentiation Marker) Recombinant Rabbit Monoclonal Antibody (clone:F"
Filaggrin is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules. Active filaggrin is present at a level of the epidermis where keratinocytes are in transition between the live nucleated granular layer and the anucleate cornified layer, sµggesting that filaggrin aids in the terminal differentiation process by facilitating apoptotic machinery. Protein function: Aggregates keratin intermediate filaments and promotes disulfide-bond formation among the intermediate filaments during terminal differentiation of mammalian epidermis. [The UniProt Consortium]
Keywords: Anti-FLG, Anti-Filaggrin, Anti-Filaggrin (Keratinocyte Differentiation Marker) Recombinant Rabbit Monoclonal Antibody (Clone:FLG/1957R)
Supplier: Abeomics
Supplier-Nr: 12-1181

Properties

Application: IHC
Antibody Type: Monoclonal
Clone: FLG/1957R
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: Recombinant fragment of human Filaggrin protein (aa 198-288) (exact sequence is proprietary)
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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