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![Anti-Fibronectin receptor/ VLA-5, clone NKI-SAM1 (Monoclonal) [Mouse]](/custom/plugins/NetiThemeBiomol/Resources/Themes/Frontend/Biomol/frontend/_public/src/img/no-picture.jpg)
| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| MON-MON1034 | 1 ml | - | - |
Request delivery time estimate |
174.00€
|
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
MON1034 recognizes a 150/130 kD receptor for fibronectin, (VLA-alpha-5 protein from the integrin... more
Product information "Anti-Fibronectin receptor/ VLA-5, clone NKI-SAM1 (Monoclonal) [Mouse]"
MON1034 recognizes a 150/130 kD receptor for fibronectin, (VLA-alpha-5 protein from the integrin superfamily of antigens). The antibody reacts with platelets, lymphocytes, monocytes and most cell lines including K562 and U937. Protein function: Integrin alpha-5/beta-1 (ITGA5:ITGB1) is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. ITGA5:ITGB1 binds to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1 (PubMed:18635536, PubMed:25398877). ITGA5:ITGB1 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1 (PubMed:12807887, PubMed:17158881). ITGA5:ITGB1 is a receptor for IL1B and binding is essential for IL1B signaling (PubMed:29030430). ITGA5:ITGB3 is a receptor for soluble CD40LG and is required for CD40/CD40LG signaling (PubMed:31331973). [The UniProt Consortium]
| Keywords: | Anti-FNRA, Mouse anti-Fibronectin receptor/ VLA-5, clone NKI-SAM1 (Monoclonal) |
| Supplier: | MONOSAN |
| Supplier-Nr: | MON1034 |
Properties
| Application: | IHC |
| Antibody Type: | Monoclonal |
| Clone: | NKI-SAM1 |
| Conjugate: | No |
| Host: | Mouse |
| Species reactivity: | human |
Database Information
| KEGG ID : | K06484 | Matching products |
| UniProt ID : | P08648 | Matching products |
| Gene ID | GeneID 3678 | Matching products |
Handling & Safety
| Storage: | +4°C |
| Shipping: | +4°C (International: °C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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