Item number Size Datasheet Manual SDS Delivery time Quantity Price
A303-891A-T 20 µl (2 blots) -

3 - 9 business days*

A303-891A-M 100 µl (10 blots) -

3 - 9 business days*

A303-891A 100 µl (100 µg) -

3 - 9 business days*

Protein function: S-adenosyl-L-methionine-dependent methyltransferase that has the ability to... more
Product information "Anti-Fibrillarin"
Protein function: S-adenosyl-L-methionine-dependent methyltransferase that has the ability to methylate both RNAs and proteins. Involved in pre-rRNA processing by catalyzing the site-specific 2'-hydroxyl methylation of ribose moieties in pre-ribosomal RNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA. Also acts as a protein methyltransferase by mediating methylation of 'Gln-105' of histone H2A (H2AQ104me), a modification that impairs binding of the FACT complex and is specifically present at 35S ribosomal DNA locus (PubMed:24352239). [The UniProt Consortium]
Keywords: Anti-FBL, Anti-FIB1, EC=2.1.1.-, Anti-Histone-glutamine methyltransferase, Anti-34 kDa nucleolar scleroderma antigen, Anti-rRNA 2'-O-methyltransferase fibrillarin
Supplier: Bethyl Laboratories
Supplier-Nr: A303-891A


Application: WB, IP
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human, Mouse (Expected: Bovine, Dog, Horse, Rabbit, Guinea Pig_10141, Pig, Panda, Orangutan, Rhesus Monkey, Gorilla, Chimpanzee, White-tufted-ear Marmoset, Green Monkey, Crab-eating Macaque, African Elephant, Northern White-cheeked Gibbon)
Immunogen: synthetic peptide. The epitope recognized by A303-891A-T maps to a region between residue 271 and 321 of human Fibrillarin using the numbering given in entry NP_001427.2 (GeneID 2091).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Our products are for laboratory research use only: Not for administration to humans!
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