Anti-Fibrillarin

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A303-890A-T	10 µl (10 µg)		-		2 - 8 business days*		164.00€
A303-890A	100 µl (100 µg)		-		2 - 8 business days*		588.00€

If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk

Protein function: S-adenosyl-L-methionine-dependent methyltransferase that has the ability to... more

Close menu

Product information "Anti-Fibrillarin"

Protein function: S-adenosyl-L-methionine-dependent methyltransferase that has the ability to methylate both RNAs and proteins. Involved in pre-rRNA processing by catalyzing the site-specific 2'-hydroxyl methylation of ribose moieties in pre-ribosomal RNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA. Also acts as a protein methyltransferase by mediating methylation of 'Gln-105' of histone H2A (H2AQ104me), a modification that impairs binding of the FACT complex and is specifically present at 35S ribosomal DNA locus (PubMed:24352239). [The UniProt Consortium]

Keywords:	Anti-FBL, Anti-FIB1, EC=2.1.1.-, Anti-Histone-glutamine methyltransferase, Anti-34 kDa nucleolar scleroderma antigen, Anti-rRNA 2'-O-methyltransferase fibrillarin
Supplier:	Bethyl Laboratories
Supplier-Nr:	A303-890A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse (Expected: rat)
Immunogen:	synthetic peptide. The epitope recognized by A303-890A-T maps to a region between residue 1 and 50 of human Fibrillarin using the numbering given in entry NP_001427.2 (GeneID 2091).
Format:	Antigen Affinity Purified