Anti-FGFR1 (Y463) (Basic Fibroblast Growth Factor Receptor 1, FGFR-1, bFGF-R, Proto-oncogene c-Fgr,

Anti-FGFR1 (Y463) (Basic Fibroblast Growth Factor Receptor 1, FGFR-1, bFGF-R, Proto-oncogene c-Fgr,
Item number Size Datasheet Manual SDS Delivery time Quantity Price
F4305-08F-FITC.200 200 µl - -

3 - 19 business days*

993.00€
 
FGFR1 is a member of the fibroblast growth factor receptor family, where amino acid sequence is... more
Product information "Anti-FGFR1 (Y463) (Basic Fibroblast Growth Factor Receptor 1, FGFR-1, bFGF-R, Proto-oncogene c-Fgr,"
FGFR1 is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction. Mutations in this gene can lead to Pfeiffer syndrome and Jackson-Weiss syndrome. Applications: Suitable for use in FLISA and Western Blot. Other applications not tested. Recommended Dilution: FLISA: 1:1,000, Western Blot: 1:50-1:100, Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap., , Note: Applications are based on unconjugated antibody.
Keywords: Anti-BFGFR, Anti-CD331, Anti-N-sam, Anti-FGFR1, Anti-FLT-2, Anti-FGFR-1, Anti-bFGF-R-1, EC=2.7.10.1, Anti-Proto-oncogene c-Fgr, Anti-Fms-like tyrosine kinase 2, Anti-Fibroblast growth factor receptor 1, Anti-Basic fibroblast growth factor receptor 1
Supplier: United States Biological
Supplier-Nr: F4305-08F-FITC

Properties

Application: FLISA, WB
Antibody Type: Polyclonal
Conjugate: FITC
Host: Rabbit
Species reactivity: human
Immunogen: Synthetic peptide corresponding to amino acid residues surrounding Y463 of human FGFR1 (KLH).
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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