Anti-FGFR1-Y307 (FGFR1, BFGFR, CEK, FGFBR, FLG, FLT2, HBGFR, Fibroblast growth factor receptor 1, Ba

Anti-FGFR1-Y307 (FGFR1, BFGFR, CEK, FGFBR, FLG, FLT2, HBGFR, Fibroblast growth factor receptor 1, Ba
Item number Size Datasheet Manual SDS Delivery time Quantity Price
035633-HRP.200 200 µl - -

3 - 19 business days*

721.00€
 
The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR)... more
Product information "Anti-FGFR1-Y307 (FGFR1, BFGFR, CEK, FGFBR, FLG, FLT2, HBGFR, Fibroblast growth factor receptor 1, Ba"
The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction. Mutations in this gene have been associated with Pfeiffer syndrome, Jackson-Weiss syndrome, Antley-Bixler syndrome, osteoglophonic dysplasia, and autosomal dominant Kallmann syndrome 2. Chromosomal aberrations involving this gene are associated with stem cell myeloproliferative disorder and stem cell leukemia lymphoma syndrome. Applications: Suitable for use in Western Blot, ELISA, Recommended Dilution: ELISA: 1:1,000, Western Blot: 1:100-500, Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. , , Note: Applications are based on unconjugated antibody.
Keywords: Anti-BFGFR, Anti-CD331, Anti-N-sam, Anti-FGFR1, Anti-FLT-2, Anti-FGFR-1, Anti-bFGF-R-1, EC=2.7.10.1, Anti-Proto-oncogene c-Fgr, Anti-Fms-like tyrosine kinase 2, Anti-Fibroblast growth factor receptor 1, Anti-Basic fibroblast growth factor receptor 1
Supplier: United States Biological
Supplier-Nr: 035633-HRP

Properties

Application: ELISA, WB
Antibody Type: Polyclonal
Conjugate: HRP
Host: Rabbit
Reactivity: Human
Immunogen: FGFR1-Y307 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Y307 region of human FGFR1.
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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