Anti-FBXW4, CT (FBXW4, FBW4, SHFM3, F-box/WD repeat-containing protein 4, Dactylin, F-box and WD-40

Anti-FBXW4, CT (FBXW4, FBW4, SHFM3, F-box/WD repeat-containing protein 4, Dactylin, F-box and WD-40
Item number Size Datasheet Manual SDS Delivery time Quantity Price
035572-HRP.200 200 µl - -

3 - 19 business days*

721.00€
 
This gene is a member of the F-box/WD-40 gene family, which recruit specific target proteins... more
Product information "Anti-FBXW4, CT (FBXW4, FBW4, SHFM3, F-box/WD repeat-containing protein 4, Dactylin, F-box and WD-40"
This gene is a member of the F-box/WD-40 gene family, which recruit specific target proteins through their WD-40 protein-protein binding domains for ubiquitin mediated degradation. In mouse, a highly similar protein is thought to be responsible for maintaining the apical ectodermal ridge of developing limb buds, disruption of the mouse gene results in the absence of central digits, underdeveloped or absent metacarpal/metatarsal bones and syndactyly. This phenotype is remarkably similar to split hand-split foot malformation in humans, a clinically heterogeneous condition with a variety of modes of transmission. An autosomal recessive form has been mapped to the chromosomal region where this gene is located, and complex rearrangements involving duplications of this gene and others have been associated with the condition. A pseudogene of this locus has been mapped to one of the introns of the BCR gene on chromosome 22. Applications: Suitable for use in Western Blot, ELISA, Recommended Dilution: ELISA: 1:1,000, Western Blot: 1:100-500, Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. , , Note: Applications are based on unconjugated antibody.
Keywords: Anti-FBW4, Anti-FBXW4, Anti-Dactylin, Anti-F-box/WD repeat-containing protein 4, Anti-F-box and WD-40 domain-containing protein 4
Supplier: United States Biological
Supplier-Nr: 035572-HRP

Properties

Application: ELISA, WB
Antibody Type: Polyclonal
Conjugate: HRP
Host: Rabbit
Reactivity: Human
Immunogen: FBXW4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 341-370 amino acids from the C-terminal region of human FBXW4.
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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