Anti-FBXO11, NT (FBXO11, FBX11, VIT1, F-box only protein 11, Vitiligo-associated protein 1) (Azide f

Anti-FBXO11, NT (FBXO11, FBX11, VIT1, F-box only protein 11, Vitiligo-associated protein 1) (Azide f
Item number Size Datasheet Manual SDS Delivery time Quantity Price
035548-FITC.200 200 µl - -

3 - 19 business days*

721.00€
 
This gene encodes a member of the F-box protein family which is characterized by an approximately... more
Product information "Anti-FBXO11, NT (FBXO11, FBX11, VIT1, F-box only protein 11, Vitiligo-associated protein 1) (Azide f"
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. It can function as an arginine methyltransferase that symmetrically dimethylates arginine residues, and it acts as an adaptor protein to mediate the neddylation of p53, which leads to the suppression of p53 function. This gene is known to be down-regulated in melanocytes from patients with vitiligo, a skin disorder that results in depigmentation. Polymorphisms in this gene are associated with chronic otitis media with effusion and recurrent otitis media (COME/ROM), a hearing loss disorder, and the knockout of the homologous mouse gene results in the deaf mouse mutant Jeff (Jf), a single gene model of otitis media. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Applications: Suitable for use in Western Blot, FLISA, Recommended Dilution: FLISA: 1:1,000, Western Blot: 1:100-500, Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. , , Note: Applications are based on unconjugated antibody.
Keywords: Anti-VIT-1, Anti-FBX11, Anti-FBXO11, Anti-UG063H01, Anti-F-box only protein 11, Anti-Vitiligo-associated protein 1, Anti-Protein arginine N-methyltransferase 9
Supplier: United States Biological
Supplier-Nr: 035548-FITC

Properties

Application: FLISA, WB
Antibody Type: Polyclonal
Conjugate: FITC
Host: Rabbit
Reactivity: Human
Immunogen: FBXO11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 54-83 amino acids from the N-terminal region of human FBXO11.
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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