Anti-FADD, ID (FADD, MORT1, Protein FADD, Mediator of receptor induced toxicity, FAS-associated deat

Anti-FADD, ID (FADD, MORT1, Protein FADD, Mediator of receptor induced toxicity, FAS-associated deat
Item number Size Datasheet Manual SDS Delivery time Quantity Price
035335-HRP.200 200 µl - -

3 - 19 business days*

721.00€
 
The protein encoded by this gene is an adaptor molecule that interacts with various cell surface... more
Product information "Anti-FADD, ID (FADD, MORT1, Protein FADD, Mediator of receptor induced toxicity, FAS-associated deat"
The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development. Applications: Suitable for use in Western Blot, ELISA, Recommended Dilution: ELISA: 1:1,000, Western Blot: 1:100-500, Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. , , Note: Applications are based on unconjugated antibody.
Keywords: Anti-FADD, Anti-GIG3, Anti-MORT1, Anti-Protein FADD, Anti-Growth-inhibiting gene 3 protein, Anti-FAS-associated death domain protein, Anti-Mediator of receptor induced toxicity, Anti-FAS-associating death domain-containing protein
Supplier: United States Biological
Supplier-Nr: 035335-HRP

Properties

Application: ELISA, WB
Antibody Type: Polyclonal
Conjugate: HRP
Host: Rabbit
Reactivity: Human
Immunogen: FADD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 106-135 amino acids from the Central region of human FADD.
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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