Anti-Factor IX

Factor IX is one of the key factors for blood coagulation. It can be transformed into two-chained activated form (FactorIXa) by factors in both coagulation pathways: by Factor XIa of the contact pathway or by Factor VIIa of the tissue factor pathway. In the presence of Factor VII cofactor, Ca++ and membrane phospholipids, Factor IXa activates Factor X. The activated Factor X (Factor Xa) triggers the transformation of prothrombin to thrombin, thus results in blood coagulation. Hemophilia B is a disease caused by Factor IX deficiency. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilutions: Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.