Item number Size Datasheet Manual SDS Delivery time Quantity Price
A303-973A-T 20 µl (2 blots) -

3 - 9 business days*

A303-973A-M 100 µl (10 blots) -

3 - 9 business days*

A303-973A 100 µl (100 µg) -

3 - 9 business days*

Protein function: Mediates the nuclear export of aminoacylated tRNAs. In the nucleus binds to... more
Product information "Anti-Exportin-T"
Protein function: Mediates the nuclear export of aminoacylated tRNAs. In the nucleus binds to tRNA and to the GTPase Ran in its active GTP- bound form. Docking of this trimeric complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins. Upon transit of a nuclear export complex into the cytoplasm, disassembling of the complex and hydrolysis of Ran-GTP to Ran-GDP (induced by RANBP1 and RANGAP1, respectively) cause release of the tRNA from the export receptor. XPOT then return to the nuclear compartment and mediate another round of transport. The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. [The UniProt Consortium]
Keywords: Anti-XPOT, Anti-Exportin-T, Anti-tRNA exportin, Anti-Exportin(tRNA)
Supplier: Bethyl Laboratories
Supplier-Nr: A303-973A


Application: WB, IP
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human (Expected: Mouse, Orangutan)
Immunogen: synthetic peptide. The epitope recognized by A303-973A-T maps to a region between residue 912 to 962 of human Exportin, tRNA using the numbering given in entry NP_009166.2 (GeneID 11260).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Our products are for laboratory research use only: Not for administration to humans!
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