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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
A303-973A-T | 10 µl (10 µg) | - |
2 - 8 business days* |
164.00€
|
|||
A303-973A | 100 µl (100 µg) | - |
2 - 8 business days* |
588.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Mediates the nuclear export of aminoacylated tRNAs. In the nucleus binds to... more
Product information "Anti-Exportin-T"
Protein function: Mediates the nuclear export of aminoacylated tRNAs. In the nucleus binds to tRNA and to the GTPase Ran in its active GTP- bound form. Docking of this trimeric complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins. Upon transit of a nuclear export complex into the cytoplasm, disassembling of the complex and hydrolysis of Ran-GTP to Ran-GDP (induced by RANBP1 and RANGAP1, respectively) cause release of the tRNA from the export receptor. XPOT then return to the nuclear compartment and mediate another round of transport. The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. [The UniProt Consortium]
Keywords: | Anti-XPOT, Anti-Exportin-T, Anti-tRNA exportin, Anti-Exportin(tRNA) |
Supplier: | Bethyl Laboratories |
Supplier-Nr: | A303-973A |
Properties
Application: | WB, IP |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human (Expected: mouse, orangutan) |
Immunogen: | synthetic peptide. The epitope recognized by A303-973A-T maps to a region between residue 912 to 962 of human Exportin, tRNA using the numbering given in entry NP_009166.2 (GeneID 11260). |
Format: | Antigen Affinity Purified |
Database Information
KEGG ID : | K14288 | Matching products |
UniProt ID : | O43592 | Matching products |
Gene ID | GeneID 11260 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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