Anti-EXOSC9

Anti-EXOSC9
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-R35793-100UG 100 µg - -

3 - 10 business days*

755.00€
 
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s)... more
Product information "Anti-EXOSC9"
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Exosome component 9, PMSCL1 Protein function: Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes. EXOSC9 binds to ARE-containing RNAs. [The UniProt Consortium]
Keywords: Anti-PMSCL1, Anti-EXOSC9, Anti-PM/Scl-75, Anti-Exosome component 9, Anti-Autoantigen PM/Scl 1, Anti-Exosome complex component RRP45, Anti-Polymyositis/scleroderma autoantigen 1, Anti-Polymyositis/scleroderma autoantigen 75 kDa, EXOSC9 Antibody
Supplier: NSJ Bioreagents
Supplier-Nr: R35793

Properties

Application: WB, ELISA (peptide)
Antibody Type: Polyclonal
Conjugate: No
Host: Goat
Species reactivity: human
Immunogen: Amino acids RTQTTSAKQEKAP were used as the immunogen for this EXOSC9 antibody.
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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