Anti-Estrogen Receptor (ER)

Anti-Estrogen Receptor (ER)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
E3565-06L.100 100 µg - -

3 - 19 business days*

594.00€
 
Estrogen Receptor alpha is a 65kD protein and a member of the steroid family of nuclear... more
Product information "Anti-Estrogen Receptor (ER)"
Estrogen Receptor alpha is a 65kD protein and a member of the steroid family of nuclear receptors. Estrogen Receptor alpha is a ligand-activated transcription factor that, when bound to estrogen, induces a conformational change that allows dimerization and binding to estrogen response element sequences. When bound to DNA, Estrogen Receptor alpha can positively or negatively regulate gene transcription. Like other steroid hormone receptors, Estrogen Receptors are intracellular proteins. Estrogen Receptors play an important role in regulating mammary gland growth and differentiation. Breast tumors that are ER positive may also show a more favorable response to anti-estrogen therapies, Applications: Suitable for use in Western Blot and Immunoprecipitation. Other applications not tested. Recommended Dilution: Western Blot: 1:250, Immunoprecipitation: 15ug/ml only Immunoprecipates the active receptor., Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Supplier: United States Biological
Supplier-Nr: E3565-06L

Properties

Application: IP, WB
Antibody Type: Monoclonal
Clone: 8k114
Conjugate: No
Host: Mouse
Reactivity: Human
Immunogen: Synthetic peptide: RAANLWPSPLMIKR conjugated to KLH, corresponding to amino acids 287-300 of Human Estrogen Receptor. Epitope: hinge region
Purity: Purified by Protein G affinity chromatography.
Format: Affinity Purified

Database Information

Handling & Safety

Storage: -20°C (-20°C Glycerol)
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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