Anti-ERAP1

Anti-ERAP1
Item number Size Datasheet Manual SDS Delivery time Quantity Price
600-401-BB5 100 µg - -

6 - 10 business days*

684.00€
 
Anti-ERAP1 Antibody was affinity purified from monospecific antiserum by immunoaffinity... more
Product information "Anti-ERAP1"
Anti-ERAP1 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. ERAP1 antibody is human and mouse reactive. At least two isoforms of ERAP1 are known to exist, this antibody will detect both isoforms. ERAP1 antibody is predicted to not cross-react with ERAP2. Protein function: Aminopeptidase that plays a central role in peptide trimming, a step required for the generation of most HLA class I- binding peptides. Peptide trimming is essential to customize longer precursor peptides to fit them to the correct length required for presentation on MHC class I molecules. Strongly prefers substrates 9-16 residues long. Rapidly degrades 13-mer to a 9-mer and then stops. Preferentially hydrolyzes the residue Leu and peptides with a hydrophobic C-terminus, while it has weak activity toward peptides with charged C-terminus. May play a role in the inactivation of peptide hormones. May be involved in the regulation of blood pressure through the inactivation of angiotensin II and/or the generation of bradykinin in the kidney. [The UniProt Consortium]
Keywords: Anti-A-LAP, Anti-ERAP1, Anti-APPILS, Anti-ARTS-1, Anti-PILS-AP, EC=3.4.11.-, Anti-Aminopeptidase PILS, Anti-Endoplasmic reticulum aminopeptidase 1, Anti-Adipocyte-derived leucine aminopeptidase, Anti-Puromycin-insensitive leucyl-specific aminopeptidase
Supplier: Rockland Immunochemicals
Supplier-Nr: 600-401-BB5

Properties

Application: ELISA, IHC, IFM, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse
Immunogen: 19 amino acid peptide near the C-terminus of human ERAP.
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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