Anti-ER-alpha

Anti-ER-alpha
Item number Size Datasheet Manual SDS Delivery time Quantity Price
030186.100 100 µl - -

3 - 19 business days*

381.00€
 
The estrogen receptor (ER) is a ligand-activated transcription factor composed of several domains... more
Product information "Anti-ER-alpha"
The estrogen receptor (ER) is a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. Alternative splicing results in several ER mRNA transcripts, which differ primarily in their 5-prime untranslated regions. Two isoforms of the human ER, ERA and ER-beta, occur, each with distinct tissue and cell patterns of expression. Pelletier and El-Alfy (2000) studied the immunocytochemical localization of ESRA and ESRB in human reproductive tissues. In the ovary, ERB immunoreactivity was found in nuclei of granulosa cells of growing follicles at all stages from primary to mature follicles, interstitial gland, and germinal epithelium cells. Nuclear staining for ERA occurred in thecal, interstitial gland, and germinal epithelium cells. In the uterus, strong ERA immunoreactivity was detected in nuclei of epithelial, stromal, and muscle cells. Applications: Western Bloting: 1:500-1:2000., Immunohistochemistry: 1:200-1:1000., ELISA: Suggested dilution 1:10000., Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: Anti-ER, Anti-ESR, Anti-ESR1, Anti-ER-alpha, Anti-Estrogen receptor, Anti-Estradiol receptor, Anti-Nuclear receptor subfamily 3 group A member 1
Supplier: United States Biological
Supplier-Nr: 030186

Properties

Application: ELISA, IHC, WB
Antibody Type: Monoclonal
Clone: 13B264
Conjugate: No
Host: Mouse
Reactivity: Human
Immunogen: Purified recombinant fragment of human ER-alpha (410-592aa) expressed in E. coli.

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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