Anti-EPHA5 (Ephrin Type-A Receptor 5, Tyrosine-protein Kinase Receptor EHK-1, Eph Homology Kinase-1,

Anti-EPHA5 (Ephrin Type-A Receptor 5, Tyrosine-protein Kinase Receptor EHK-1, Eph Homology Kinase-1,
Item number Size Datasheet Manual SDS Delivery time Quantity Price
E3363-01A-AP.200 200 µl - -

3 - 19 business days*

819.00€
 
EPHA5 belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and... more
Product information "Anti-EPHA5 (Ephrin Type-A Receptor 5, Tyrosine-protein Kinase Receptor EHK-1, Eph Homology Kinase-1,"
EPHA5 belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families). Applications: Suitable for use in ELISA, Western Blot, and Immunohistochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:4,000, Western Blot: 1:2,000, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Do not freeze alkaline phosphatase conjugates which could result in a substantial loss of enzymatic activity. Light sensitive. Aliquots are stable for at least 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap., , Note: Applications are based on unconjugated antibody.
Supplier: United States Biological
Supplier-Nr: E3363-01A-AP

Properties

Application: ELISA, IHC, WB
Antibody Type: Monoclonal
Clone: 10i34
Conjugate: No
Host: Mouse
Reactivity: Human
Format: Affinity Purified

Database Information

UniProt ID : P54756 | Find alternatives

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: °C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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