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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
030163.100 | 100 µl | - | - |
3 - 19 business days* |
719.00€
|
eIF4E, a protein modulates translation of maternal mRNAs in early embryos before the onset of... more
Product information "Anti-EIF4E"
eIF4E, a protein modulates translation of maternal mRNAs in early embryos before the onset of zygotic transcription. eIF4E also influences the overall rate of translation. eIF4E binds to the 7 methyl GTP cap structure of eukaryotic mRNAs. Phosphorylation of eIF4E on serine 209 regulates the affinity of this protein for the 7 methyl GTP cap and/or RNA. Phosphorylation also enhances the interaction of eIF4E with eIF4G, which form a complex known as eIF4F. eIF4E phosphorylation is correlated with increased translational rate in a number of cell types. Several kinases are currently being investigated as potential regulators of eIF4E including PKC and/or the MAP kinase activated Mnk. Applications: Western Bloting: 1:500-1:2000., Immunohistochemistry: 1:200-1:1000., Immunofluorescence: 1:200-1:1000., Flow cytometry: 1:200-1:400., ELISA: Suggested dilution 1:10000., Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: | Anti-eIF4E, Anti-EIF4E, Anti-eIF-4E, Anti-EIF4EL1, Anti-eIF-4F 25 kDa subunit, Anti-mRNA cap-binding protein, Anti-Eukaryotic translation initiation factor 4E |
Supplier: | United States Biological |
Supplier-Nr: | 030163 |
Properties
Application: | ELISA, FC, IHC, WB |
Antibody Type: | Monoclonal |
Clone: | 13B241 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human |
Immunogen: | Purified recombinant fragment of human EIF4E expressed in E. coli. |
Database Information
KEGG ID : | K03259 | Matching products |
UniProt ID : | P06730 | Matching products |
Gene ID | GeneID 1977 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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