Anti-EIF3J

Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-AB-65594.60 60 µl -

7 - 16 business days*

198.00€
E-AB-65594.120 120 µl -

7 - 16 business days*

317.00€
E-AB-65594.200 200 µl -

7 - 16 business days*

525.00€
 
This gene encodes a core subunit of the eukaryotic initiation factor 3 complex, which... more
Product information "Anti-EIF3J"
This gene encodes a core subunit of the eukaryotic initiation factor 3 complex, which participates in the initiation of translation by aiding in the recruitment of protein and mRNA components to the 40S ribosome. There are pseudogenes for this gene on chromosomes 1, 3, and 9. Alternative splicing results in multiple transcript variants encoding different isoforms. Protein function: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis (PubMed:25849773, PubMed:27462815). The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression (PubMed:25849773). [The UniProt Consortium]
Keywords: Anti-eIF3j, Anti-PRO0391, Anti-eIF3 p35, Anti-eIF-3-alpha, Anti-Eukaryotic translation initiation factor 3 subunit 1, Anti-Eukaryotic translation initiation factor 3 subunit J, EIF3J Polyclonal Antibody
Supplier: Elabscience
Supplier-Nr: E-AB-65594

Properties

Application: WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse
Immunogen: Recombinant protein of human EIF3J

Handling & Safety

Storage: -20°C
Shipping: 4°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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