Anti-EIF3B

Anti-EIF3B
Promotion:

For a limited time, purchase an Elabscience primary antibody (size 60 μl and up) and receive a free secondary antibody of the same size.

*1
*1 Offer expires 30/04/2020
Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-AB-63318.60 60 µl - -

7 - 16 business days

119.00€
E-AB-63318.120 120 µl - -

7 - 16 business days

211.00€
E-AB-63318.200 200 µl - -

7 - 16 business days

367.00€
 
Protein function: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3)... more
Product information "Anti-EIF3B"
Protein function: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis (PubMed:9388245, PubMed:17581632, PubMed:25849773, PubMed:27462815). The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation (PubMed:9388245, PubMed:17581632). The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression (PubMed:25849773). [The UniProt Consortium]
Keywords: Anti-hPrt1, Anti-eIF3b, Anti-eIF3 p116, Anti-eIF3 p110, Anti-eIF-3-eta, Anti-Prt1 homolog, Anti-Eukaryotic translation initiation factor 3 subunit 9, Anti-Eukaryotic translation initiation factor 3 subunit B, EIF3B Polyclonal Antibody
Supplier: Elabscience
Supplier-Nr: E-AB-63318-60µL

Properties

Application: WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein of human EIF3B

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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