Anti-EIF3A

Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-AB-62282.60 60 µl -

7 - 16 business days*

198.00€
E-AB-62282.120 120 µl -

7 - 16 business days*

317.00€
E-AB-62282.200 200 µl -

7 - 16 business days*

525.00€
 
Protein function: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3)... more
Product information "Anti-EIF3A"
Protein function: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis (PubMed:17581632, PubMed:25849773). The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation (PubMed:17581632, PubMed:11169732). The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression (PubMed:25849773, PubMed:27462815). [The UniProt Consortium]
Keywords: Anti-eIF3a, Anti-eIF3 p180, Anti-eIF3 p167, Anti-eIF3 p185, Anti-eIF-3-theta, Anti-Eukaryotic translation initiation factor 3 subunit A, Anti-Eukaryotic translation initiation factor 3 subunit 10, EIF3A Polyclonal Antibody
Supplier: Elabscience
Supplier-Nr: E-AB-62282

Properties

Application: WB, IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat
Immunogen: Recombinant protein of human EIF3A

Handling & Safety

Storage: -20°C
Shipping: 4°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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