Anti-Dicer

Anti-Dicer
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A301-936A-T 10 µl (10 µg) -

2 - 8 business days*

164.00€
A301-936A 100 µl (100 µg) -

2 - 8 business days*

588.00€
 
Protein function: Double-stranded RNA (dsRNA) endoribonuclease playing a central role in short... more
Product information "Anti-Dicer"
Protein function: Double-stranded RNA (dsRNA) endoribonuclease playing a central role in short dsRNA-mediated post-transcriptional gene silencing. Cleaves naturally occurring long dsRNAs and short hairpin pre-microRNAs (miRNA) into fragments of twenty-one to twenty-three nucleotides with 3' overhang of two nucleotides, producing respectively short interfering RNAs (siRNA) and mature microRNAs. SiRNAs and miRNAs serve as guide to direct the RNA- induced silencing complex (RISC) to complementary RNAs to degrade them or prevent their translation. Gene silencing mediated by siRNAs, also called RNA interference, controls the elimination of transcripts from mobile and repetitive DNA elements of the genome but also the degradation of exogenous RNA of viral origin for instance. The miRNA pathway on the other side is a mean to specifically regulate the expression of target genes. [The UniProt Consortium]
Keywords: Anti-DICER, Anti-DICER1, EC=3.1.26.3, Anti-Helicase MOI, Anti-Endoribonuclease Dicer, Anti-Helicase with RNase motif
Supplier: Bethyl Laboratories
Supplier-Nr: A301-936A

Properties

Application: WB, IP
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse (Expected: rat, dog, guinea pig_10141, pig, panda, orangutan, rhesus monkey, gorilla, chimpanzee, west indian ocean coelacanth, white-tufted-ear marmoset, crab-eating macaque, african elephant, northern white-cheeked gibbon)
Immunogen: synthetic peptide. The epitope recognized by A301-936A-T maps to a region between residue 600 and 650 of human double-stranded RNA-specific endoribonuclease, dicer1 using the numbering given in entry NP_085124.2 (GeneID 23405).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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