DHX37 is a member of the DEAH box family of proteins that possesses several conserved motifs which include the highly conserved DEAH (Asp-Glu-Ala-His) amino acid sequence motif. The major activity of DEAH box proteins is to function as ATP-dependent RNA helicases. RNA helicases play an important role in all aspects of RNA metabolism and function which include pre-mRNA splicing, RNA synthesis, RNA degradation, RNA export, RNA translation, RNA secondary structure formation, ribosome biogenesis, and the assembly of RNP complexes. The specific function of DHX37 has not been determined. Alternate names for DHX33 include putative ATP-dependent RNA helicase DHX37, DEAH box protein 37, DDX37, KIAA1517, MGC2695, MGC4322, MGC46245, and FLJ41974.
synthetic peptide. The epitope recognized by A300-856A-T maps to a region between residue 1 and 50 of human DEAH (Asp-Glu-Ala-His) Box Protein 37 using the numbering given in entry NP_116045.2 (GeneID 57647).