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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ABE-10-7539-25 | 25 µg | - |
3 - 11 business days* |
149.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
DSG3 (Desmoglein 3) is a calcium-binding transmembrane glycoprotein component of desmosomes,... more
Product information "Anti-Desmoglein 3 (Clone: ABM4A31)"
DSG3 (Desmoglein 3) is a calcium-binding transmembrane glycoprotein component of desmosomes, conferring strong cell-cell adhesion. Desmosomes are button-like points of intercellular contact that allow the attachment of cytoskeletal elements to the plasma membrane at sites of cell-cell adhesion. DSG3 is expressed in basal and immediate suprabasal layers of skin. To maintain cell-cell adhesion DSG3 interacts with other desmosomal proteins, such as plakoglobin. Plakoglobin is closely related to Beta-catenin, which is a well-known downstream effector molecule in the canonical Wnt signaling pathway.DSG3 also promotes cancer cell growth and invasion through a plakoglobin-mediated signaling pathway. Protein function: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. [The UniProt Consortium]
Keywords: | Anti-PVA, Anti-DSG3, Anti-CDHF6, Anti-Desmoglein-3, Anti-Cadherin family member 6, Anti-130 kDa pemphigus vulgaris antigen, Monoclonal Antibody to Desmoglein 3 (Clone: ABM4A31) |
Supplier: | Abeomics |
Supplier-Nr: | 10-7539-25 |
Properties
Application: | IHC |
Antibody Type: | Monoclonal |
Clone: | ABM4A31 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human |
Immunogen: | A partial length recombinant Desmoglein 3 protein (amino acids 328-526) was used as the immunogen for this antibody. |
Format: | Purified |
Database Information
KEGG ID : | K07598 | Matching products |
UniProt ID : | P32926 | Matching products |
Gene ID | GeneID 1830 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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