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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ARG53993.100 | 100 µl | - | - |
6 - 14 business days* |
624.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Core component of the DBIRD complex, a multiprotein complex that acts at the... more
Product information "Anti-DBC1, clone 3G4-D11-D7"
Protein function: Core component of the DBIRD complex, a multiprotein complex that acts at the interface between core mRNP particles and RNA polymerase II (RNAPII) and integrates transcript elongation with the regulation of alternative splicing: the DBIRD complex affects local transcript elongation rates and alternative splicing of a large set of exons embedded in (A + T)-rich DNA regions. Inhibits SIRT1 deacetylase activity leading to increasing levels of p53/TP53 acetylation and p53-mediated apoptosis. Inhibits SUV39H1 methyltransferase activity. As part of a histone H3- specific methyltransferase complex may mediate ligand-dependent transcriptional activation by nuclear hormone receptors. Plays a critical role in maintaining genomic stability and cellular integrity following UV-induced genotoxic stress. Regulates the circadian expression of the core clock components NR1D1 and ARNTL/BMAL1. Enhances the transcriptional repressor activity of NR1D1 through stabilization of NR1D1 protein levels by preventing its ubiquitination and subsequent degradation. [The UniProt Consortium]
Keywords: | Anti-DBC1, Anti-CCAR2, Anti-DBC.1, Anti-DBC-1, Anti-p30 DBC, Anti-DBIRD complex subunit KIAA1967, Anti-Deleted in breast cancer gene 1 protein, Anti-Cell cycle and apoptosis regulator protein 2, Anti-Cell division cycle and apoptosis regulator protein 2 |
Supplier: | Arigo Biolaboratories |
Supplier-Nr: | ARG53993 |
Properties
Application: | WB, ICC, IF, IP |
Antibody Type: | Monoclonal |
Clone: | 3G4-D11-D7 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human, mouse, rat, monkey |
Immunogen: | Purified recombinant human DBC1 protein fragments expressed in E.coli |
Format: | Affinity Purified |
Database Information
UniProt ID : | Q8N163 | Matching products |
Gene ID | GeneID 57805 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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