Anti-DAXX

Anti-DAXX
Item number Size Datasheet Manual SDS Delivery time Quantity Price
030139.100 100 µl - -

3 - 19 business days*

477.00€
 
DAXX (death-domain associated protein), it is a multifunctional protein that resides in multiple... more
Product information "Anti-DAXX"
DAXX (death-domain associated protein), it is a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants. Applications: Western Bloting: 1:500-1:2000., Immunofluorescence: 1:200-1:1000., Flow cytometry: 1:200-1:400., ELISA: Suggested dilution 1:10000., Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: Anti-EAP1, Anti-DAXX, Anti-Daxx, Anti-hDaxx, Anti-BING2, Anti-ETS1-associated protein 1, Anti-Death domain-associated protein 6, Anti-Fas death domain-associated protein
Supplier: United States Biological
Supplier-Nr: 030139

Properties

Application: ELISA, FC, WB
Antibody Type: Monoclonal
Clone: 13B217
Conjugate: No
Host: Mouse
Reactivity: Human
Immunogen: Purified recombinant fragment of human DAXX expressed in E. coli.

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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