Anti-Cytokeratin 5

Anti-Cytokeratin 5
Item number Size Datasheet Manual SDS Delivery time Quantity Price
030136.100 100 µl - -

3 - 19 business days*

477.00€
 
Cytokeratin 5, also known as CK5, KRT5. It is a member of the keratin gene family. Biochemically,... more
Product information "Anti-Cytokeratin 5"
Cytokeratin 5, also known as CK5, KRT5. It is a member of the keratin gene family. Biochemically, most members of the CK family fall into one of two classes, type I (acidic polypeptides) and type II (basic polypeptides). The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. At least one member of the acidic family and one member of the basic family is expressed in all epithelial cells. Cytokeratin 5 is expressed in normal basal cells. Mutations of the Cytokeratin5 gene (KRT5) have been shown to result in the autosomal dominant disorderepidermolysis bullosa (EB). Defects in KRT5 are a cause of epidermolysis bullosa simplex. Applications: Western Bloting: 1:500-1:2000., ELISA: Suggested dilution 1:10000., Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: Anti-K5, Anti-KRT5, Anti-CK-5, Anti-Keratin-5, Anti-Cytokeratin-5, Anti-58 kDa cytokeratin, Anti-Type-II keratin Kb5, Anti-Keratin, type II cytoskeletal 5
Supplier: United States Biological
Supplier-Nr: 030136

Properties

Application: ELISA, WB
Antibody Type: Monoclonal
Clone: 13B214
Conjugate: No
Host: Mouse
Reactivity: Human
Immunogen: Purified recombinant fragment of Cytokeratin 5 expressed in E. coli.

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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