Anti-Cytokeratin 17 (C-Term) Rabbit

Anti-Cytokeratin 17 (C-Term) Rabbit
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay32275-100 100 µl -

6 - 10 business days*

480.00€
 
Cytokeratin 17 (CK-17) is an intermediate filament protein and a member of the cytokeratin... more
Product information "Anti-Cytokeratin 17 (C-Term) Rabbit"
Cytokeratin 17 (CK-17) is an intermediate filament protein and a member of the cytokeratin protein family encoded by KRT17 in humans. It is a type I acidic cytokeratin expressed in the basal cells of epithelial appendages, such as hair follicles and sebaceous glands, and is localized to the cytoplasm. CK-17 expression can be induced in the epidermis under conditions of cellular stress, such as viral infection, injury, or psoriasis. CK-17 is also expressed in squamous, basal, and urothelial carcinomas, as well as adenocarcinomas, and is associated with poor prognosis in breast, cervical, oral squamous, and gastric carcinomas. Heterozygous dominant mutations in KRT17 are associated with early onset alopecia. Missense mutations in KRT17 are associated with ectodermal dysplasias, including pachyonychia congenita and steatocystoma multiplex. Cayman's Cytokeratin 17 (C-Term) Rabbit Monoclonal Antibody can be used for immunohistochemistry (IHC) and Western blot (WB) applications.Synonyms: CK-17, Keratin-17, Keratin, Type II Cytoskeletal 17, KRT17. Immunogen: Peptide from the C-terminal region of human cytokeratin 17. Clone Designation: RM351. Formulation: (Request formulation change), 100 µl of protein A-affinity purified monoclonal antibody. Storage Buffer: PBS with 50% glycerol, 1% BSA, and 0.09% sodium azide. Host: Rabbit. Isotype: IgG. Applications: IHC, WB. Cross Reactivity: (+) Cytokeratin 17.
Keywords: CK-17, Keratin, Type II Cytoskeletal 17, Keratin-17, KRT17
Supplier: Cayman Chemical
Supplier-Nr: 32275

Properties

Application: IHC, WB
Antibody Type: Monoclonal
Clone: RM351
Conjugate: No
Host: Rabbit
Immunogen: Peptide from the C-terminal region of human cytokeratin 17
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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