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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| ARG43123.50 | 50 µg | - | - |
6 - 14 business days* |
520.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and... more
Product information "Anti-CYP11A1"
Protein function: A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones (PubMed:21636783). Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal (PubMed:21636783). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the second into a water molecule. Two electrons are provided by NADPH via a two-protein mitochondrial transfer system comprising flavoprotein FDXR (adrenodoxin/ferredoxin reductase) and nonheme iron-sulfur protein FDX1 or FDX2 (adrenodoxin/ferredoxin) (PubMed:21636783). {ECO:0000269, PubMed:21636783}. [The UniProt Consortium]
| Keywords: | Anti-CYP11A, Anti-CYPXIA1, Anti-CYPXIA1, Anti-Cytochrome P450 11A1, Anti-Cytochrome P450(scc), Anti-Cytochrome P450 11A1, Anti-Cytochrome P450(scc), Anti-Cholesterol desmolase, Anti-Cholesterol desmolase, Anti-Cholesterol side-chain cleavage enzyme, mitoc |
| Supplier: | Arigo Biolaboratories |
| Supplier-Nr: | ARG43123 |
Properties
| Application: | IHC (frozen), IHC (paraffin), WB |
| Antibody Type: | Polyclonal |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | human |
| Immunogen: | Synthetic peptide corresponding to aa. 507-521 of Human CYP11A1. (ISFTFWPFNQEATQQ) |
| MW: | 60 kD |
| Format: | Antigen Affinity Purified |
Database Information
| KEGG ID : | K00498 | Matching products |
| UniProt ID : | P05108 | Matching products |
| Gene ID | GeneID 1583 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: °C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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