Anti-CUL2, NT (CUL2, Cullin-2) (Azide free) (APC)

Anti-CUL2, NT (CUL2, Cullin-2) (Azide free) (APC)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
034364-APC.200 200 µl - -

3 - 19 business days*

993.00€
 
Core component of multiple cullin-RING-based ECS (ElonginB/C-CUL2/5-SOCS-box protein) E3... more
Product information "Anti-CUL2, NT (CUL2, Cullin-2) (Azide free) (APC)"
Core component of multiple cullin-RING-based ECS (ElonginB/C-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of target proteins. May serve as a rigid scaffold in the complex and may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The E3 ubiquitin-protein ligase activity of the complex is dependent on the neddylation of the cullin subunit and is inhibited by the association of the deneddylated cullin subunit with TIP120A/CAND1 (By similarity). The functional specificity of the ECS complex depends on the substrate recognition component. ECS(VHL) mediates the ubiquitination of hypoxia-inducible factor (HIF). Applications: Suitable for use in Western Blot, FLISA, Recommended Dilution: FLISA: 1:1,000, Western Blot: 1:100-500, Storage and Stability: Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap., , Note: Applications are based on unconjugated antibody.
Keywords: Anti-CUL2, Anti-CUL-2, Anti-Cullin-2
Supplier: United States Biological
Supplier-Nr: 034364-APC

Properties

Application: FLISA, WB
Antibody Type: Polyclonal
Conjugate: APC
Host: Rabbit
Species reactivity: human, mouse
Immunogen: CUL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 149-179 amino acids from the N-terminal region of human CUL2.
Format: Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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