Anti-Cul2 (IHC)

Anti-Cul2 (IHC)
Promotion:

Bethyl is giving away a free permanent marker for every Bethyl purchase until supplies last!

Item number Size Datasheet Manual SDS Delivery time Quantity Price
IHC-00692-T 10 µl (5+ slides) -

3 - 9 business days

125.00€
IHC-00692 100 µl (50+ slides) -

3 - 9 business days

456.00€
 
Protein function: Core component of multiple cullin-RING-based ECS (ElonginB/C-CUL2/5-SOCS-box... more
Product information "Anti-Cul2 (IHC)"
Protein function: Core component of multiple cullin-RING-based ECS (ElonginB/C-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of target proteins. ECS complexes and ARIH1 collaborate in tandem to mediate ubiquitination of target proteins (PubMed:27565346). May serve as a rigid scaffold in the complex and may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The E3 ubiquitin-protein ligase activity of the complex is dependent on the neddylation of the cullin subunit and is inhibited by the association of the deneddylated cullin subunit with TIP120A/CAND1. The functional specificity of the ECS complex depends on the substrate recognition component. ECS(VHL) mediates the ubiquitination of hypoxia-inducible factor (HIF). [The UniProt Consortium]
Keywords: Anti-CUL2, Anti-CUL-2, Anti-Cullin-2
Supplier: Bethyl Laboratories
Supplier-Nr: IHC-00692-T

Properties

Application: IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human, Mouse (Expected: Rat, Bovine, Dog, Horse, Guinea Pig, Panda, Orangutan, Rhesus Monkey, Gorilla, Chimpanzee, White-tufted-ear Marmoset, Crab-eating Macaque, African Elephant, Chinese Hamster, Northern White-cheeked Gibbon)
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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