Anti-CTCF

Anti-CTCF
Item number Size Datasheet Manual SDS Delivery time Quantity Price
030125.100 100 µl - -

3 - 19 business days*

477.00€
 
This gene is a member of the BORIS + CTCF gene family and encodes a transcriptional regulator... more
Product information "Anti-CTCF"
This gene is a member of the BORIS + CTCF gene family and encodes a transcriptional regulator protein with 11 highly conserved zinc finger (ZF) domains. This nuclear protein is able to use different combinations of the ZF domains to bind different DNA target sequences and proteins. Depending upon the context of the site, the protein can bind a histone acetyltransferase (HAT)-containing complex and function as a transcriptional activator or bind a histone deacetylase (HDAC)-containing complex and function as a transcriptional repressor. If the protein is bound to a transcriptional insulator element, it can block communication between enhancers and upstream promoters, thereby regulating imprinted expression. Mutations in this gene have been associated with invasive breast cancers, prostate cancers, and Wilms' tumors.Tissue specificity: Ubiquitous. Absent in primary spermatocytes. Applications: Western Bloting: 1:500-1:2000., ELISA: Suggested dilution 1:10000., Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: Anti-CTCF, Anti-CTCFL paralog, Anti-CCCTC-binding factor, Anti-11-zinc finger protein, Anti-Transcriptional repressor CTCF
Supplier: United States Biological
Supplier-Nr: 030125

Properties

Application: ELISA, WB
Antibody Type: Monoclonal
Clone: 13B203
Conjugate: No
Host: Mouse
Reactivity: Human, Monkey
Immunogen: Purified recombinant fragment of human CTCF expressed in E. coli.

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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