Anti-CrkRS

Anti-CrkRS
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A301-679A-T 20 µl (2 blots) -

3 - 9 business days

125.00€
A301-679A-M 100 µl (10 blots) -

3 - 9 business days

299.00€
A301-679A 100 µl (100 µg) -

3 - 9 business days

443.00€
 
Protein function: Cyclin-dependent kinase that phosphorylates the C- terminal domain (CTD) of the... more
Product information "Anti-CrkRS"
Protein function: Cyclin-dependent kinase that phosphorylates the C- terminal domain (CTD) of the large subunit of RNA polymerase II (POLR2A), thereby acting as a key regulator of transcription elongation. Regulates the expression of genes involved in DNA repair and is required for the maintenance of genomic stability. Preferentially phosphorylates 'Ser-5' in CTD repeats that are already phosphorylated at 'Ser-7', but can also phosphorylate 'Ser-2'. Required for RNA splicing, possibly by phosphorylating SRSF1/SF2. Involved in regulation of MAP kinase activity, possibly leading to affect the response to estrogen inhibitors. [The UniProt Consortium]
Keywords: Anti-CRK7, Anti-CrkRS, Anti-CDK12, Anti-hCDK12, EC=2.7.11.22, EC=2.7.11.23, Anti-Cyclin-dependent kinase 12, Anti-CDC2-related protein kinase 7, Anti-Cell division protein kinase 12, Anti-Cdc2-related kinase, arginine/serine-rich
Supplier: Bethyl Laboratories
Supplier-Nr: A301-679A

Properties

Application: WB, IP
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human (Expected: Mouse, Rat)
Immunogen: synthetic peptide. The epitope recognized by A301-679A-M maps to a region between residue 1 and 50 of human cell division cycle 2 (CDC2)-related kinase arginine/serine-rich using the numbering given in entry NP_057591.2 (GeneID 51755).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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